Matthew Bates


Matthew at the summit of Mount Chacaltaya, Bolivia; 2001
Matthew Bates is a co-founder and secretary of Apex and coordinated the largest drug trial ever conducted at high altitude during the second Apex expedition. He is a Wellcome Trust Clinical Research Fellow and Honorary Specialist Registrar in Cardiology in Newcastle upon Tyne.

Recent publications:

1. Quantifying the challenges of specialty training: the 2013 British Junior Cardiologists' Association survey.

Sohaib SA, Bates MG, Sarwar R, Holdsworth D.
Br J Hosp Med (Lond). 2014 Jul;75(7):402-5. PMID: 25040520

2. Network analysis reveals distinct clinical syndromes underlying acute mountain sickness.

Hall DP, MacCormick IJ, Phythian-Adams AT, Rzechorzek NM, Hope-Jones D, Cosens S, Jackson S, Bates MG, Collier DJ, Hume DA, Freeman T, Thompson AA, Baillie JK.
PLoS One. 2014 Jan 22;9(1):e81229. PMID: 24465370

3. Discrete gait characteristics are associated with m.3243A>G and m.8344A>G variants of mitochondrial disease and its pathological consequences.

Galna B, Newman J, Jakovljevic DG, Bates MG, Schaefer AM, McFarland R, Turnbull DM, Trenell MI, Gorman GS, Rochester L.
J Neurol. 2014 Jan;261(1):73-82. PMID: 24150688

4. Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease.

Bates MG, Newman JH, Jakovljevic DG, Hollingsworth KG, Alston CL, Zalewski P, Klawe JJ, Blamire AM, MacGowan GA, Keavney BD, Bourke JP, Schaefer A, McFarland R, Newton JL, Turnbull DM, Taylor RW, Trenell MI, Gorman GS.
Int J Cardiol. 2013 Oct 9;168(4):3599-608. PMID: 23742928

5. Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.

Hollingsworth KG, Willis TA, Bates MG, Dixon BJ, Lochmuller H, Bushby K, Bourke J, MacGowan GA, Straub V.
Eur J Heart Fail. 2013 Sep;15(9):986-94. PMID: 23576288

6. Video-assisted thoracoscopic left ventricular pacing in patients with and without previous sternotomy.

Nelson KE, Bates MG, Turley AJ, Linker NJ, Owens WA.
Ann Thorac Surg. 2013 Mar;95(3):907-13. PMID: 23313472

7. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers.

Bates MG, Hollingsworth KG, Newman JH, Jakovljevic DG, Blamire AM, MacGowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS.
Eur Heart J Cardiovasc Imaging. 2013 Jul;14(7):650-8. PMID: 23129433

8. Cardiac involvement in mitochondrial DNA disease: clinical spectrum, diagnosis, and management.

Bates MG, Bourke JP, Giordano C, d'Amati G, Turnbull DM, Taylor RW.
Eur Heart J. 2012 Dec;33(24):3023-33. PMID: 22936362

9. Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study.

Hollingsworth KG, Macgowan GA, Morris L, Bates MG, Taylor R, Jones DE, Newton JL, Blamire AM.
J Appl Physiol (1985). 2012 Jun;112(12):2043-8. PMID: 22461446

10. Mitochondrial respiratory chain disease in children undergoing cardiac transplantation: a prospective study.

Bates MG, Nesbitt V, Kirk R, He L, Blakely EL, Alston CL, Brodlie M, Hasan A, Taylor RW, McFarland R.
Int J Cardiol. 2012 Mar 8;155(2):305-6. PMID: 22188990

11. Sildenafil citrate for the prevention of high altitude hypoxic pulmonary hypertension: double blind, randomized, placebo-controlled trial.

Bates MG, Thompson AA, Baillie JK, Sutherland AI, Irving JB, Hirani N, Webb DJ.
High Alt Med Biol. 2011 Fall;12(3):207-14. PMID: 21962063

12. Do implantable cardioverter defibrillators improve survival in patients with severe left ventricular systolic dysfunction after coronary artery bypass graft surgery?

Fazal IA, Bates MG, Matthews IG, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Jun;12(6):1010-6. PMID: 21398652

13. In patients undergoing aortic valve replacement, what factors predict the requirement for permanent pacemaker implantation?

Matthews IG, Fazal IA, Bates MG, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Mar;12(3):475-9. PMID: 21138915

14. Postoperative permanent pacemaker implantation in patients undergoing trans-catheter aortic valve implantation: what is the incidence and are there any predicting factors?

Bates MG, Matthews IG, Fazal IA, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):243-53. PMID: 21098508

15. Large thrombus burden in acute myocardial infarction: successful use of distal protection device following failure of thrombus aspiration.

Bates MG, Matthews IG, Hall JA.
Heart. 2010 Sep;96(17):1371. PMID: 20801855

16. The citric acid cough threshold and the ventilatory response to carbon dioxide on ascent to high altitude.

Thompson AA, Baillie JK, Bates MG, Schnopp MF, Simpson A, Partridge RW, Drummond GB, Mason NP.
Respir Med. 2009 Aug;103(8):1182-8. PMID: 19303278

17. Oral antioxidant supplementation does not prevent acute mountain sickness: double blind, randomized placebo-controlled trial.

Baillie JK, Thompson AA, Irving JB, Bates MG, Sutherland AI, Macnee W, Maxwell SR, Webb DJ.
QJM. 2009 May;102(5):341-8. PMID: 19273551

18. Endogenous urate production augments plasma antioxidant capacity in healthy lowland subjects exposed to high altitude.

Baillie JK, Bates MG, Thompson AA, Waring WS, Partridge RW, Schnopp MF, Simpson A, Gulliver-Sloan F, Maxwell SR, Webb DJ.
Chest. 2007 May;131(5):1473-8. PMID: 17494796

19. Phosphodiesterase type 5 inhibitors in the treatment and prevention of high altitude pulmonary edema.

Bates MG, Thompson AA, Baillie JK.
Curr Opin Investig Drugs. 2007 Mar;8(3):226-31. PMID: 17408118