Matthew Bates


Matthew at the summit of Mount Chacaltaya, Bolivia; 2001
Matthew Bates is a co-founder and secretary of Apex and coordinated the largest drug trial ever conducted at high altitude during the second Apex expedition. He is a Wellcome Trust Clinical Research Fellow and Honorary Specialist Registrar in Cardiology in Newcastle upon Tyne.

Recent publications:

1. Subepicardial dysfunction leads to global left ventricular systolic impairment in patients with limb girdle muscular dystrophy 2I.

Hollingsworth KG, Willis TA, Bates MG, Dixon BJ, Lochmuller H, Bushby K, Bourke J, Macgowan GA, Straub V.
Eur J Heart Fail. 2013 Apr 10. PMID: 23576288

2. Video-assisted thoracoscopic left ventricular pacing in patients with and without previous sternotomy.

Nelson KE, Bates MG, Turley AJ, Linker NJ, Owens WA.
Ann Thorac Surg. 2013 Mar;95(3):907-13. doi: 10.1016/j.athoracsur.2012.11.022. PMID: 23313472

3. Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers.

Bates MG, Hollingsworth KG, Newman JH, Jakovljevic DG, Blamire AM, Macgowan GA, Keavney BD, Chinnery PF, Turnbull DM, Taylor RW, Trenell MI, Gorman GS.
Eur Heart J Cardiovasc Imaging. 2012 Nov 4. PMID: 23129433

4. Cardiac involvement in mitochondrial DNA disease: clinical spectrum, diagnosis, and management.

Bates MG, Bourke JP, Giordano C, d'Amati G, Turnbull DM, Taylor RW.
Eur Heart J. 2012 Dec;33(24):3023-33. doi: 10.1093/eurheartj/ehs275. PMID: 22936362

5. Cardiac torsion-strain relationships in fatigued primary biliary cirrhosis patients show accelerated aging: a pilot cross-sectional study.

Hollingsworth KG, Macgowan GA, Morris L, Bates MG, Taylor R, Jones DE, Newton JL, Blamire AM.
J Appl Physiol. 2012 Jun;112(12):2043-8. doi: 10.1152/japplphysiol.00195.2012. PMID: 22461446

6. Mitochondrial respiratory chain disease in children undergoing cardiac transplantation: a prospective study.

Bates MG, Nesbitt V, Kirk R, He L, Blakely EL, Alston CL, Brodlie M, Hasan A, Taylor RW, McFarland R.
Int J Cardiol. 2012 Mar 8;155(2):305-6. doi: 10.1016/j.ijcard.2011.11.063. PMID: 22188990

7. Sildenafil citrate for the prevention of high altitude hypoxic pulmonary hypertension: double blind, randomized, placebo-controlled trial.

Bates MG, Thompson AA, Baillie JK, Sutherland AI, Irving JB, Hirani N, Webb DJ.
High Alt Med Biol. 2011 Fall;12(3):207-14. doi: 10.1089/ham.2011.0007. PMID: 21962063

8. Do implantable cardioverter defibrillators improve survival in patients with severe left ventricular systolic dysfunction after coronary artery bypass graft surgery?

Fazal IA, Bates MG, Matthews IG, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Jun;12(6):1010-6. doi: 10.1510/icvts.2010.259465. PMID: 21398652

9. In patients undergoing aortic valve replacement, what factors predict the requirement for permanent pacemaker implantation?

Matthews IG, Fazal IA, Bates MG, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Mar;12(3):475-9. doi: 10.1510/icvts.2010.254607. PMID: 21138915

10. Postoperative permanent pacemaker implantation in patients undergoing trans-catheter aortic valve implantation: what is the incidence and are there any predicting factors?

Bates MG, Matthews IG, Fazal IA, Turley AJ.
Interact Cardiovasc Thorac Surg. 2011 Feb;12(2):243-53. doi: 10.1510/icvts.2010.256578. PMID: 21098508

11. Large thrombus burden in acute myocardial infarction: successful use of distal protection device following failure of thrombus aspiration.

Bates MG, Matthews IG, Hall JA.
Heart. 2010 Sep;96(17):1371. doi: 10.1136/hrt.2010.201533. PMID: 20801855

12. The citric acid cough threshold and the ventilatory response to carbon dioxide on ascent to high altitude.

Thompson AA, Baillie JK, Bates MG, Schnopp MF, Simpson A, Partridge RW, Drummond GB, Mason NP.
Respir Med. 2009 Aug;103(8):1182-8. doi: 10.1016/j.rmed.2009.02.007. PMID: 19303278

13. Oral antioxidant supplementation does not prevent acute mountain sickness: double blind, randomized placebo-controlled trial.

Baillie JK, Thompson AA, Irving JB, Bates MG, Sutherland AI, Macnee W, Maxwell SR, Webb DJ.
QJM. 2009 May;102(5):341-8. doi: 10.1093/qjmed/hcp026. PMID: 19273551

14. Endogenous urate production augments plasma antioxidant capacity in healthy lowland subjects exposed to high altitude.

Baillie JK, Bates MG, Thompson AA, Waring WS, Partridge RW, Schnopp MF, Simpson A, Gulliver-Sloan F, Maxwell SR, Webb DJ.
Chest. 2007 May;131(5):1473-8. PMID: 17494796

15. Phosphodiesterase type 5 inhibitors in the treatment and prevention of high altitude pulmonary edema.

Bates MG, Thompson AA, Baillie JK.
Curr Opin Investig Drugs. 2007 Mar;8(3):226-31. PMID: 17408118