CIRCADIAN RHYTHMS AT ALTITUDE

We are conducting a pioneering project examining the impact of individuals’ body clocks (also known as chronotype) on physiological and clinical outcomes. This addresses a key knowledge gap in wilderness medicine that affects the interpretation of previous high-altitude studies and has potentially contributed to conflicting data on interventions for preventing/treating acute mountain sickness. As well as the relevance of this research to human health in the context of jetlag and hypoxia, this will also set a new standard for chronotype-control in studies carried out in other wilderness environments.

DARK ADAPTATION AT ALTITUDE

Sight is critical for orientation, movement, and balance and so visual function is clearly essential for the safety and performance of pilots, mountaineers, and athletes training at altitude. Furthermore, as the only visible part of the brain, studying retinal function at altitude provides a unique opportunity to objectively assess the effects of hypoxia on the brain. In future, changes in retinal function may be used as a new variable in field research on altitude sickness, which was not available previously owing to the impractical nature of traditional methods of measuring dark adaptation. This is an exciting field of research, with
the potential to benefit those exposed to hypoxia due to both environment and illness.

ALTITUDE AND THE MENSTRUAL CYCLE

This project aims to investigate the link between hypoxia inducible factor (hif) 1 alpha and menstrual blood loss, following on from the work of Edinburgh researcher Dr Jackie Maybin. This will involve female participants self-analysing blood volumes using pictograms and analysis of blood samples collected over the course of this research project. This work is especially relevant to women experiencing the very common condition of heavy menstrual bleeding.

SOPHIE HATTERSLEY

Expedition Leader 

Sophie is a fifth year medical student at the University of Edinburgh. As well as leading the expedition, Sophie will be undertaking research into the pathophysiology of high-altitude pulmonary oedema (HAPE). Her academic interests are in expedition medicine, trauma and surgery. Outside of studying, Sophie is a keen photographer, and loves travelling the globe in search of the perfect shot; Bolivia, Peru, Malaysia and Indonesia to name a few. Having been inspired by the amazing team on Apex 5 to lead her own expedition, she can’t wait for all the hard work to pay off. It’ll be great to be back in the beautiful Bolivian Andes, doing cutting edge research and inspiring a new generation!

DENISA STRONCEKOVA

Logistics Coordinator 

Denisa is a fifth year medical student at the university of Edinburgh, and a lover of travelling, food and salsa dancing. Having taken part in the APEX 5 expedition as a volunteer, Denisa is very enthusiastic to undertake the committee role for APEX 6 as a Logistics Coordinator. Being half-Peruvian and a fluent Spanish speaker, South America is a continent that has always drawn her in.  An adventurer who enjoys challenges, Denisa is looking forward to travelling back into the remote terrains of Bolivia, this time with an exciting aim of conducting research alonside fellow commmitte member Sarah,  on how night vision is affected by altitude.

OLIVER VICK 

Logistics Coordinator

Oliver is a senior medical student in charge of the Expedition Operations for APEX 6. He will be making sure everything is ready for us flying out, and that the expedition runs safely and smoothly. A keen traveller, Oliver will have been to 55 countries before APEX 6 as well as every continent besides Antarctica! Through travelling, as well as other areas, he has gained extensive experience in getting people and equipment from A to B. Aside from travelling, Oliver has an active interest in health policy, healthcare management, events management and politics. Oliver is not yet planning to undertake any research on the expedition, instead focussing on organisational aspects, but may yet be open to persuasion!

ERIN BENNETT 

Funding Coordinator 

Erin is currently a fourth year medical student. During this expedition, she will be taking the lead on a projects. The first  investigating the effects of altitude and hypoxia on the menstrual cycle. As a volunteer on APEX5, she thoroughly enjoyed exploring South America and is looking forward to seeing more of the beautiful continent. In her spare time, Erin loves a good book (slowly making her way through some non-fiction these days) as well as walking at home in the Borders and the occasional run with Volunteer Coordinator Sarah!

ALASTAIR WOODHEAD

Funding Coordinator

Alastair is a fourth year medical student at the University of Edinburgh, who developed a keen interest in expedition medicine as a volunteer on the APEX 5 expedition. Alongside Erin, Alastair has taken on the role of Funding Coordinator. Alastair will also be undertaking a research project investigating sleep at altitude. Outside of medicine, Alastair’s interests lie in sport and spending time away from his beloved bikes will certainly be his greatest challenge! Don’t be surprised to see him hiking up Huayna Potosi in search of signal to check on the latest sporting news!

SARAH LEWIS 

Volunteer Coordinator & Publicity

Sarah is in her fifth year of medicine at the University of Edinburgh. During the APEX6 expedition she will be working alongside Denisa investigating the effects of altitude on the eye. In the committee Sarah is our Volunteer Coordinator and heads up publicity for the expedition. Sarah loves to travel - the previous APEX expedition was her first time in South America and she cannot wait to return to Bolivia and explore. Outside of medicine and APEX Sarah loves music, dancing and trying out new experiences - the latest challenges include a sky dive and a marathon!!! 

Tom Avery

One of the UK's foremost explorers

"I am proud to support APEX 6. The Bolivian mountains are amongst the more beautiful in the world, but they are also a real test of human endurance. The work of the APEX6 team will be invaluable in gaining better understanding of the effects of altitude on the human body.  I wish them a safe and successful expedition."

Sir Chris Bonington

British Mountaineer

“I am delighted to endorse APEX 6. APEX has been hugely successful over the past years, with much exciting research being done into the intricate effects of altitude and hypoxia on the human body. This year, students will take on this challenge once again, with a further aim of collaborating with local Bolivian researchers. The group have my full support, and I wish them all the best on this journey.”